I guess you all would have seen the cool 2D animation work in the recent blockbuster Scanner Darkly. Well, if you want to have the same effect applied to your photographs, now you can, thanks to this article that outlines some image tweaking applied through Adobe Illustrator to achieve the effect.
Pretty close, huh? But a lot of work, if you ask me. Have some couple hours handy if you want to work on a decent photograph.